| 单词 |
ubiquitin |
| 释义 |
ubiquitin, n. Biochem.
Brit. |juːˈbɪkwɪtɪn|, |jʊˈbɪkwɪtɪn|, U.S. |juˈbɪkwədɪn|
[‹ ubiquit- (in ubiquitous adj.) + -in suffix1.]
A single-chain polypeptide, present in all eukaryotic organisms in a highly conserved form, which functions to label harmful, defective, or superfluous proteins for degradation by the proteasome.
1975Clin. Bull. 5 66 (title) Thymopoietin, ubiquitin and the differentiation of lymphocytes. 1975D. H. Schlesinger et al. in Biochemistry 14 2214 Ubiquitin (formerly ubiquitous immunopoietic polypeptide or UBIP) is a 8451-dalton polypeptide. 1984E. Holtzman & A. B. Novikoff Cells & Organelles (ed. 3) ii. viii. 231 The nonlysosomal system selectively degrades those proteins to which a polypeptide called ubiquitin has been linked. 1990Nucleic Acids Res. 18 6449 A remarkable 72 out of 76 amino acid residues are invariant in the ubiquitins of fungi, plants and vertebrates. 2004Washington Post (Home ed) 7 Oct. a3/4 When a protein is slated for removal, a long string of ubiquitin molecules attaches to it. |
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