“spirolactone”的英文意思_释义_用法

单词

spirolactone

释义

spirolactone Chem. and Pharm.|spaɪrəʊˈlæktəʊn|
[f. spiro- 2 + lactone 2.]
Any spirane in which one of the rings is a lactone; spec. any of the series of steroid derivatives to which spironolactone belongs.
1958Canad. Med. Assoc. Jrnl. LXXIX. 883/1 The administration of Spirolactone results in a persistent and significant increase in sodium excretion.1959Jrnl. Org. Chem. XXIV. 743/1 The spirolactone side chain was built onto a steriod nucleus containing an aromatic A ring.1961Lancet 16 Sept. 618/2 With the development of the 17-spirolactones, which are aldosterone antagonists, a new method has become available for investigating possible cases of primary aldosteronism.1970Passmore & Robson Compan. Med. Stud. II. xi. 10/1 The main reason for believing that spirolactones are aldosterone antagonists is that they reverse all the renal effects of aldosterone.

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