| 单词 |
pteroic |
| 释义 |
pteroic, a. Biochem.|ˈtɛrəʊɪk|
[f. pteridine + -oic.]
pteroic acid: a synthetic crystalline solid from which the pteroylglutamic acids are formally derived by peptidic linkage of glutamic acid residues to the carboxyl group; p-(2-amino-4-hydroxypteridin-6-ylmethyl) aminobenzoic acid, C14H12N6O3.
1946[see pteroylglutamic a. a]. 1954A. White et al. Princ. Biochem. xii. 263 The linkage coupling the p-aminobenzoic acid..and glutamic acid is a peptide bond. Hydrolysis of this bond gives pteroic acid and glutamic acid. 1963W. Shive in Florkin & Stotz Comprehensive Biochem. XI. vii. 90 Among the synthetic derivatives, pteroic acid, because it is effective in replacing folic acid for S[treptococcus] faecalis R but not for L[actobacillus] casei, and the pteroyldiglutamate..are of biological interest. 1970T. Shiota in Ibid. XXI. 126 The mechanism involving successive additions of l-glutamic acid residues to pteroic acid and folic acid is supported by the work of Griffin and Brown. |
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