“pamaquin”的英文意思_释义_用法

单词

pamaquin

释义

pamaquin Pharm.|ˈpæməkwɪn|
Also -ine.
[f. pentyl + amino- + methoxy- + -a- + quinoline.]
An orange-yellow crystalline salt, C₁₉H₂₉N₃O.C₂₃H₁₆O₆, which is a toxic compound formerly used in the treatment of malaria. Cf. Plasmochin, Plasmoquine.
1941Brit. Pharmacopœia 1932 Add. iv. 24 Pamaquin is the 6-methoxy-8-[ω-diethylamino-α-methylbutyl]-aminoquinoline salt of 2:2′-dihydroxy-1:1′ -dinaphthylmethane-3:3′-dicarboxylic acid.1951A. Grollman Pharmacol. & Therapeutics xxxiii. 483 Because of its toxicity and the availability of safer and better drugs, pamaquine is no longer of therapeutic importance.1961New Scientist 4 May 261/1 The anti-malarial drugs pamaquin and primaquine produce anaemia in certain susceptible persons.1974B. G. Maegraith in A. W. Woodruff Med. in Tropics ii. 65/1 The 8-aminoquinoline most widely given [for vivax malaria] is primaquine; pamaquine or quinocide are alternatives.

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