“nitrofurantoin”的英文意思_释义_用法

单词

nitrofurantoin

释义

nitrofurantoin Pharm.|ˌnaɪtrəʊfjʊəˈræntəʊɪn|
[f. nitro- + fur-furyl (f. furfur-ol + -yl) + hydantoïn in the chemical name of the compound, 1-(5-nitrofurfurylideneamino)-hydantoïn.]
A yellow crystalline bicyclic compound, C₈H₆N₄O₅, which is an antibacterial agent used in treating infections of the urinary tract.
1953Antibiotics & Chemotherapy III. 151 A new anti⁓bacterial nitrofuran, Furadantin, Eaton, brand of nitrofurantoin.1963Amer. Rev. Respiratory Dis. LXXXVIII. 712/2 Most tubercle bacilli with increased resistance to isoniazid also manifest increased susceptibility to nitrofurantoin.1972M. Rowland in Melmon & Morrelli Clin. Pharmacol. ii. 30/2 The most common side effect associated with nitrofurantoin is gastrointestinal irritation and occasional emesis due to a central action of the drug, probably dependent on high concentrations of nitrofurantoin in blood.

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