“levallorphan”的英文意思_释义_用法

单词

levallorphan

释义

levallorphan, n. Pharm.|ˌliːvəˈlɔːfæn|
[f. levo- + allyl n. + morphine n. + -an, elements of the systematic name.]
A morphine analogue and opioid antagonist, C₁₉H₂₅NO , given intravenously (usu. as the tartrate) to counteract some of the depressant effects of certain narcotics.
1953Anesthesiology XIV. 550 Levallorphan is the generic name of 3-hydroxy-N-allylmorphan and was originally designated as R₀ 1-7700.1977Drug Metabolism & Disposition V. 273 Narcotic antagonists, naloxone, nalorphine, levallorphan, and naltrexone, specifically inhibited morphine glucuronidation.1988Biol. Abstr. LXXXV. xi. ab929/1 Neuroleptanalgesia was performed by intravenous injection of fentanyl and levallorphan 5 minutes before local anesthesia.1989Martindale's Extra Pharmacopoeia (ed. 29) 84 2/2 Levallorphan reverses severe opioid-induced respiratory depression but may exacerbate respiratory such as that induced by alcohol or other non-opioid central depressants.

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