| Acronym | Definition |
|---|
| USD | United States Dollar (currency of the USA) |
| USD | University of South Dakota |
| USD | University of San Diego (California) |
| USD | Under Secretary of Defense |
| USD | Unified School District |
| USD | US Digital (motion control; robotics company) |
| USD | Upside Down (bike suspension) |
| USD | Unified Service Desk (software) |
| USD | Unified Service Desk (Microsoft) |
| USD | User'S Supplementary Documents |
| USD | Unicenter Service Desk |
| USD | Universal Service Directive (EU) |
| USD | Office of the Under Secretary of Defense |
| USD | Universal Share Downloader (computer program download manager) |
| USD | Utah School for the Deaf |
| USD | Urban Sanitary District (UK) |
| USD | Universal Slave Driver (digital sync device) |
| USD | Union Sanitary District (Tri-Cities, CA) |
| USD | Unit Synthetische Drugs (Netherlands Synthetic Drug Enforcement Police) |
| USD | Unit Shutdown (power systems) |
| USD | Ultranet Storage Director |
| USD | Universal Skate Design |
| USD | Union for Sustainable Development |
| USD | Union Sociale Démocratique (French: Social Democratic Union) |
| USD | Universal Synchronous Data |
| USD | Underground Storm Drain |
| USD | Unallocated Space Descriptor (OSTA universal disk format) |
| USD | Uniform Symbol Description |
| USD | Upper Structure Dynamics |
| USD | Un-Signed Digit |
| USD | Ultimate Selling Date (products) |
| USD | User Systems Diagram |
| USD | Unified Software Distribution |
| USD | Utility Service District (Michigan) |