| Acronym | Definition |
|---|
| TESS | Transiting Exoplanet Survey Satellite (US NASA) |
| TESS | Trademark Electronic Search System (US Patent and Trademark Office) |
| TESS | the Exponential Encryption System |
| TESS | Toxic Exposure Surveillance System |
| TESS | Texas Excavation Safety System |
| TESS | Trading Edge Strategy Software |
| TESS | Tactical Engagement Simulation System |
| TESS | The Exponential Security System (RFC 1824) |
| TESS | Tsuneishi Economical Standard Ship (multipurpose bulk carrier; Japan) |
| TESS | Threatened and Endangered Species System (US Fish and Wildlife Service database) |
| TESS | The English Spelling Society (UK) |
| TESS | Tactical Environmental Support System |
| TESS | Tertiary Education Superannuation Scheme (Australia) |
| TESS | Terrorism, Espionage, Sabotage and Subversion |
| TESS | Treatment-Emergent Signs and Symptoms |
| TESS | Total Enterprise Security Service (SecureInfo Corporation) |
| TESS | TRW Environmental Safety Systems Inc. |
| TESS | Trend Enterprise Security Solution |
| TESS | Tactical Environment Support System |
| TESS | Triboelectrostatic Separation |
| TESS | Testing Evaluation of Speech Synthesis (assistive technology) |
| TESS | Training and Evaluation Support System (US FAA) |
| TESS | Target End-To-End Signature Simulation |
| TESS | Test Equipment, Strategy and Support |
| TESS | Teaching English to Spanish-Speakers |
| TESS | Tactical Electromagnetic Systems Study |
| TESS | Test & Evaluation Simulation Subsystem |
| TESS | The Enhanced Soldier System |
| TESS | Transition Efficiencies in Safeguards and Security |