| Acronym | Definition |
|---|
| SOB | Son of a Bitch |
| SOB | South Bend (Amtrak station code; South Bend, IN) |
| SOB | Sense of Belonging |
| SOB | Sons of Belial |
| SOB | Sick of Barack (politics) |
| SOB | Shortness of Breath (symptom) |
| SOB | South of the Border |
| SOB | Stop on By |
| SOB | Seventeen or Bust (computing) |
| SOB | Schedule of Benefits (insurance) |
| SOB | School Of Business |
| SOB | Special Operations Bureau (various locations) |
| SOB | Sexually Oriented Business |
| SOB | Scroll on By |
| SOB | Sexual Offences Bill |
| SOB | Scars on Broadway (band) |
| SOB | Services over Broadband |
| SOB | Sounding Object |
| SOB | Son of Beast |
| SOB | Set Of Books |
| SOB | Summary of Benefits |
| SOB | Senate Office Building |
| SOB | Styles of Beyond (band) |
| SOB | South Bend, Indiana (Amtrak code) |
| SOB | Strictly Only Brothers (band) |
| SOB | South Bend, IN (Amtrak) |
| SOB | Souls On Board |
| SOB | State Office Building |
| SOB | Side of Bed |
| SOB | Some Other Brand |
| SOB | Soggy on Bottom |
| SOB | Shrimp On the Barbie |
| SOB | Signed-Off-By |
| SOB | Small Of Back (holster) |
| SOB | Source Of Business |
| SOB | Statement of Basis |
| SOB | System-On-Board |
| SOB | Start Of Block |
| SOB | South Of Border |
| SOB | Start Of Business |
| SOB | Sons of Butcher (band) |
| SOB | Son of the Boss |
| SOB | Sailor on Board |
| SOB | Share of Business |
| SOB | Signs Of Betrayal (rock band) |
| SOB | Sick of Bush |
| SOB | Seal of Blood (gaming, World of Warcraft) |
| SOB | Silly Old Bear |
| SOB | Silly Old Bugger (British) |
| SOB | Socially Offensive Behavior (TV show) |
| SOB | Spouse of Birder |
| SOB | Sober Old Bastard (Alcoholics Anonymous slang) |
| SOB | Smelling Of Booze |
| SOB | Sober Old Biker (Alcoholics Anonymous slang) |
| SOB | Super Oralloy Bomb |
| SOB | Sober Old Bag (Alcoholics Anonymous slang) |
| SOB | Seaford-Oyster Bay Expressway (Long Island, New York) |
| SOB | South Orange Blossom (Florida street name) |
| SOB | Society of Orpheus and Bacchus (Yale University a capella group) |
| SOB | Sweet Old Bob |
| SOB | Son of Bazerk (hip hop) |
| SOB | Star Onion Brigade (game, Final Fantasy XI) |
| SOB | Short(ness) of Breath (medical) |
| SOB | South Oyster Bay (New York) |
| SOB | Slide Over Baby |
| SOB | Silly Old Bastard (Australian) |
| SOB | Same Ocean Buddy (Scuba) |
| SOB | Saecula Omnimodus Bellum |
| SOB | Space Order of Battle |
| SOB | Statement of Boredom |
| SOB | Sons of Batman |
| SOB | Balaton - Sármellék Hungary (Airport Code) |
| SOB | Société Ornithologique du Boulonnais (French: Ornithological Society of Boulogne; France) |
| SOB | Sell on Bottoms |
| SOB | Save Our Businesses (Florida tax proposal) |
| SOB | Sample Of Behavior |
| SOB | Standard Operational Bullstuff (polite form) |
| SOB | Special Operations Base |
| SOB | Stupid Old Bastard |
| SOB | Satan's Own Breedwork :-) |
| SOB | Standard Operating Business |
| SOB | Service Organisation Bureau (French: Service Organization Office) |
| SOB | Stop on Barrier |
| SOB | State Operations Budget |
| SOB | Straight Offset Binary |
| SOB | Sex Offenders Beware! (website) |
| SOB | Société Odontologique de Brest (French: Brest Dental Company; France) |
| SOB | South Omaha Boy |
| SOB | Smart Operating Business |