| Acronym | Definition |
|---|
| CORE | Congress Of Racial Equality |
| CORE | Central Operation of Resources for Educators (NASA) |
| CORE | Center for Operations Research and Econometrics |
| CORE | Conflict Resolution (US Department of the Interior) |
| CORE | Configuration Resource |
| CORE | Council Of Registrars |
| CORE | Council On Rehabilitation Education |
| CORE | Center for Organizational Excellence (various locations) |
| CORE | Communications Research |
| CORE | Controlled Requirement |
| CORE | Computing Resource |
| CORE | Core Objects Reused Everywhere |
| CORE | Connection Oriented Routing Environment |
| CORE | Council of Internet Registrars |
| CORE | Compatible Resource |
| CORE | Community Oriented Realtime Engineering |
| CORE | Contingency Response |
| CORE | Committee on Operating Rules for Information Exchange (Council for Affordable Quality Healthcare) |
| CORE | Consortium for Oceanographic Research and Education (representing U.S. oceanographic research institutions) |
| CORE | Comment on Reproductive Ethics (British) |
| CORE | Consortium on Reading Excellence |
| CORE | Connected Organizations for a Responsible Economy |
| CORE | Collaborations and Resources Group |
| CORE | Centre for OSCE Research |
| CORE | Corporate Responsibility Coalition (UK) |
| CORE | Common Redpoll (bird species common name) |
| CORE | Center for Organ Recovery and Education |
| CORE | Composite Object Reference |
| CORE | Comprehensive Online Research Education (Purdue University) |
| CORE | Common Runtime Environment |
| CORE | Centre for Organisation Research and Education (India) |
| CORE | Centers for Obesity Research and Education |
| CORE | Collaborative Reputation (security mechanism) |
| CORE | Co-Ownership of Real Estate |
| CORE | Corporate Responsibility Bill (UK) |
| CORE | Citizens of Oakland Respond to Emergencies (Oakland, CA) |
| CORE | Cosmic Orgone Engineering |
| CORE | Comprehensive Risk Evaluation |
| CORE | Center for Oceanic Research and Education |
| CORE | Challenge Of Reverse Engineering |
| CORE | Coker and Refinery Expansion (Wood River Refinery; Roxana, IL; ConocoPhillips) |
| CORE | Centre of Rehabilitation Engineering (UK) |
| CORE | Committee Organizing Rape Education |
| CORE | Conservation of Resources through Enterprise |
| CORE | Component Runtime Environment |
| CORE | Contingency Response Program |
| CORE | Controlled Requirement Expression (software) |
| CORE | Contingency Response Element (MTMC) |
| CORE | Creating Opportunities and Resources for Educators |
| CORE | Community Online Resource Exchange |
| CORE | Community Options for Rural Elders (Act of 2005) |
| CORE | Centre Oecuménique de Rencontres Européennes |
| CORE | Common Operational Research Equipment (NASA) |
| CORE | Capistrano Objectives for Reaching Excellence |
| CORE | Center on Renewable Energy |
| CORE | Cost Oriented Resource Estimating |
| CORE | Centralized Online Real-Time Exchange (banking) |
| CORE | Conventional Operational Readiness Exercise |
| CORE | Community of Roleplayers, Europa (gaming group) |
| CORE | Catalog of Research Expertise (University of Texas Health Science Center at Houston) |
| CORE | Cadre Of Response Employees (FEMA) |
| CORE | Coastal Redwoods Environmental School |
| CORE | Competent on Resist-A-Ball Education |
| CORE | Comparative Oncology Resource Exchange (Cornell University) |
| CORE | Content Online Resource Enterprise (US Army) |
| CORE | Center for Operations Research and Engineering |
| CORE | Chief Of Receive Element (formerly CORL) |
| CORE | Community of Removal Experts (spyware removal) |
| CORE | Corrected Overall Reference Equivalent (ITU-T) |
| CORE | Connection Oriented Route Establishment |
| CORE | Central Office Recovery Express (AT&T) |
| CORE | Central Office for Resources in Education |
| CORE | Children of Reentry (Community Services Initiative; North Carolina) |
| CORE | Continuous Observation & Risk Evaluation |