| 单词 |
homeodomain |
| 释义 |
homeodomain, n. Genetics and Molecular Biol.
Brit. |ˈhəʊmɪə(ʊ)də(ʊ)ˌmeɪn|, U.S. |ˈhoʊmiədoʊˈˌmeɪn|, |ˈhoʊmiədəˈˌmeɪn|
Forms: 19– homeodomain[Brit.], 19– homoeodomain[Brit.]
[‹ homœo- comb. form + domain n.]
A sequence of 60 amino acids encoded by a homeobox, forming a distinctive structural domain with a DNA-binding function in proteins involved in the regulation of transcription and translation.
1984Cell 37 412/1 The Xenopus conserved domain and the three Drosophila homeo domains might serve the same function. 1988Nature 22–9 Dec. 744/1 A combination of segmentation and homoeotic gene products, many of which contain homoeodomains, specify the developmental fates of cells in striped patterns. 1993Mechanisms Devel. 41 59/2 The α helix 2-β turn-α helix 3 sequences within the homeodomain..can be altered to those of the Dfd gene. 1998Proc. National Acad. Sci. U.S.A. 95 15450/2 The nucleotide sequence of element C is a potential binding site for interactions with homeodomain proteins. |
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